诱发IAF夹杂物与原晶粒的尺寸匹配关系

 对于氧化物冶金船板钢而言，细小弥散分布的夹杂物会对其原始晶粒产生钉扎和诱发晶内铁素体的双重作用，且研究发现诱发晶内铁素体的夹杂物尺寸与原始奥氏体晶粒尺寸存在一定的匹配关系。围绕上述问题进行了系统的分析研究和数据统计,结果表明，不同晶粒尺寸下，诱发晶内铁素体的夹杂物尺寸与原奥氏体晶粒度间存在近似线性关系，且随着奥氏体晶粒度的增大，诱发晶内铁素体的夹杂物尺寸则相应减小。     

Length–weight relationships of five catfish species (Siluriformes) from the Ganga River,India

Knowledge of the length–weight relationships (LWRs) of fish is an important tool to understand fish body form, growth pattern, stock management and their conservation. The present study focused on investigating the length–weight relationships for five catfish species, Pachypterus atherinoides (Bloch, 1794), belonging to family Horabagridae; Batasio batasio (Hamilton, 1822) family Bagridae; Bagarius yarrelli (Sykes, 1839), family Gogangra viridescens (Hamilton, 1822); and Sisor rhabdophorus (Hamilton, 1822) belonging to family Sisoridae. Specimens were collected from the middle stretch of the Ganga River in India from November 2016 to May 2018. A total of 174 specimens of five fish species were collected, and their total lengths were measured to the nearest centimetre and the body weight to the nearest gram. The value of the parameter slope (b) of LWRs of the five species ranged from 2.86 (B. yarrelli) to 3.16 (G. viridescens), with a mean value of 2.99. The results of the present study documented the new maximum total length (TL) for P. atherinoides and S. rhabdophorus. The present study also provides the first reference regarding LWRs for S. rhabdophorus.     

犹豫模糊环境下准则具有偏好关系的TODIM方法

针对智慧制造评估时专家的决策信息具有犹豫模糊不确定性问题，提出了一种关于准则具有犹豫模糊偏好关系的改进交互式多准则决策（TODIM）方法。首先提出了准则间的犹豫模糊偏好关系概念，并证明了其基本性质。在TODIM方法优势度的计算过程中，将准则权重犹豫模糊偏好关系替代原有的精确值权重，使信息的准确性最大化。将该方法用于智能制造的评估上，实例分析结果表明所提方法是可行和有效的。     

Exploring place attachment and visions of nature of water-based recreationists: the case of the longitudinal dams

This study concerns an innovative project in the Dutch river Waal: the construction of longitudinal dams. By splitting the river into a main and secondary channel, these dams significantly impact the river landscape and the way it is used by different stakeholders. We report the results of a baseline study of the expectations local water-based recreationists (fishermen and boaters) had of the longitudinal dams before they were constructed. In addition, we explore their levels of place attachment, and use the visions of nature approach to elicit their lay philosophy of nature. We found that fishermen were more strongly attached to the area than boaters. Though expectations of the dams were generally negative, this differed significantly between fishermen and boaters, and between different dimensions of landscape change. We demonstrate the relevance of place attachment and visions of nature for understanding how recreationists perceive landscape change.     

融合信任和基于概率矩阵分解的推荐算法

针对推荐精度不准确、数据稀疏、恶意推荐的问题，提出融合信任基于概率矩阵分解（PMF）的新推荐模型。首先，通过建立基于信任的协同过滤模型（CFMTS）将改进的信任机制融入到协同过滤推荐算法中。信任值通过全局信任及局部信任计算获得，其中局部信任利用了信任传播机制计算用户的直接信任值和间接信任值得到，全局信任采用信任有向图的方式计算得到。然后，将信任值与评分相似度融合以解决数据稀疏、恶意推荐的问题。同时，将CFMTS融入到PMF模型中以建立新的推荐模型——融合信任基于概率矩阵分解模型（MPMFFT），通过梯度下降算法对用户特征向量和项目特征向量进行计算以产生预测评分值，进一步提高推荐系统的精准度。通过实验将提出的MPMFFT与经典的PMF、社交信息的矩阵分解（SocialMF）、社交信息的推荐（SoRec）、加权社交信息的推荐（RSTE）等模型进行了结果的对比和分析，在公开的真实数据集Epinions上MPMFFT的平均绝对误差（MAE）和均方根误差（RMSE）比最优的RSTE模型分别降低2.9%和1.5%，同时在公开的真实数据集Ciao上MPMFFT的MAE和RMSE比最优的SocialMF模型分别降低1.1%和1.8%，结果证实了模型能在一定程度上解决数据稀疏、恶意推荐问题，有效提高推荐质量。     

Stability and antioxidant activity of anthocyanins from purple sweet potato (Ipomoea batatas L. cultivar Eshu No. 8) subjected to simulated in vitro gastrointestinal digestion

The study was aimed to investigate the stability and antioxidant activities of anthocyanins obtained from purple sweet potato via an in vitro digestion system. Three fractions of anthocyanin-rich extracts were obtained via ODS packing column. Anthocyanins and copigment (primary phenolic acids) of fraction 2 were investigated during simulated an in vitro gastrointestinal digestion. Anthocyanins and copigment were recognised by UPLC-LTQ-MS/MS. Besides, anthocyanins were found effectively stable under the acidic gastric digestion conditions. However, the anthocyanins recovery was greatly decreased at around 10% after intestinal digestion. An association between the type, number of acylated group and stability to intestinal digestion was found. Di-acylated anthocyanins possessed higher stability compared with mono-acylated anthocyanins and the stability of acylated group in digestion process followed the order of p-hydroxybenzoyl > feruloyl > caffeoyl. However, there was no much difference in copigment content which was found during digestion process. Moreover, the radical scavenging ability and xanthine oxidase (XO) inhibition showed that the digestion products possessed good biological activities mainly due to its anthocyanin composition.     

基于注意力机制与文本信息的用户关系抽取

随着社交媒体的发展,用户之间的关系网络对于社交媒体的分析有很大的帮助。因此,该文主要研究用户好友关系检测。以往的关于用户好友关系抽取的研究主要基于社交媒体上的结构化信息,比如其他好友关系,用户的不同属性等。但是,很多时候用户本身并没有大量的好友信息存在,同时也不一定有很多确定的属性。因此,我们希望基于用户发表的文本信息来对用户关系进行预测。不同于以往的潜在好友推荐算法,该文提出了一种基于注意力机制以及长短时记忆网络(long short-term memory,LSTM)的好友关系预测模型,将好友之间的评论分开处理,通过分析用户之间的评论来判断是否具备一定的好友关系。该模型将好友双方信息拼接后的结果作为输入,并将注意力机制应用于LSTM的输出。实验表明,用户之间的评论对于好友关系预测确实有较大的实际意义,该文提出的模型较之于多个基准系统的效果,取得了明显的提升。在不加入任何其它非文本特征的情况下,实验结果的准确率达到了77%。     

Synthesis and Characterization of Telmisartan-Derived Cell Death Modulators to Circumvent Imatinib Resistance in Chronic Myeloid Leukemia

New strategies to eradicate cancer stem cells in chronic myeloid leukemia (CML) include a combination of imatinib with peroxisome proliferator-activated receptor gamma (PPARγ) ligands. Recently, we identified the partial PPARγ agonist telmisartan as effective sensitizer of resistant K562 CML cells to imatinib treatment. Here, the importance of the heterocyclic core on the cell death-modulating effects of the telmisartan-derived lead 4′-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-carboxylic acid ( 3 b ) was investigated. Inspired by the pharmacodynamics of HYL-6d and the selective PPARγ ligand VSP-51, the benzimidazole was replaced by a carbazole or an indole core. The results indicate no correlation between PPARγ activation and sensitization of resistant CML cells to imatinib. The 2-COOH derivatives of the carbazoles or indoles achieved low activity at PPARγ, while the benzimidazoles showed 60-100 % activation. Among the 2-CO₂CH₃ derivatives, only the ester of the lead ( 2 b ) slightly activated PPARγ. Sensitizing effects were further observed for this non-cytotoxic 2 b (80 % cell death), and to a lesser extent for the lead 3 b or the 5-Br-substituted ester of the benzimidazoles ( 5 b ).     

生物基异己糖醇聚酯的制备及其构效关系研究进展

异己糖醇是一类碳水化合物衍生二元醇,具有高刚性、手性、亲水性和低毒等特性,在制备新型生物基、生物可降解高分子材料方面具有广阔的发展前景。围绕近年来研究较为充分的全脂肪型及半芳香型异己糖醇基均聚酯与共聚酯,综述了其合成、热学性能、力学性能、生物降解性能及潜在应用,探讨此类聚酯的高效聚合反应工艺及构效关系。异己糖醇结构单元的引入可有效提高聚合物的玻璃化转变温度,以及促进其水解和生物降解性能,在构建具有更高性能的环境友好型聚酯方面具有较高潜力,有望应用于工程塑料、纤维、生物医药等领域。此类生物基聚酯的大规模商业化需进一步开发更高效、温和的聚合反应工艺以攻克其热敏感和热降解问题。